There were no significant differences in PFC activity among three groups. Attention ability measured by trail making test A (TMT-A) was the best predictor for TUG and gait velocity. Motor functions all correlated with general cognition, attention, executive function, memory, and visuo-spatial ability. These gait and balance performance did not differ significantly between MCI and NC. Results: Individuals with MD had worse SW, CDW and TUG performance as compared to individuals with MCI and NC.
The assessment of motor function included timed up and go (TUG) test, single walking (SW), and cognitive dual task walking (CDW). The assessment of cognitive function included general cognition, attention, executive function, memory, and visuo-spatial. All participants received a comprehensive assessment including cognitive function, motor function, PFC activity during walking, and fear of fall. Methods: Normal control (NC), individuals with mild cognitive impairment (MCI) or mild dementia (MD) were enrolled in this study. This study investigated the differences in motor function and brain activity among older adults with different cognitive levels, and examined the significance of cognition on motor functions. The prefrontal cortex (PFC) as a part of the executive locomotor pathway is also important for cognitive function. 3Department of Gerontological Health Care, National Taipei University of Nursing and Health Sciences, Taipei, Taiwanīackground: Growing evidence shows the cognitive function influences the motor performance.2Department of Neurology, Taipei Municipal Gan-Dau Hospital, Taipei, Taiwan.1Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan.Wei-Han Weng 1, Yea-Ru Yang 1, Nai-Chen Yeh 1, Pei-Hsin Ku 1, Po-Shan Wang 2, Ying-Yi Liao 3 and Ray-Yau Wang 1 *
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